TV legend David Letterman teams up with fascinating global figures for in-depth interviews and curiosity-fueled excursions in this monthly talk show.
Former President Barack Obama reflects on political tensions and his family's life after the White House, and Dave visits Selma with Rep. John Lewis.
George Clooney opens up about his humanitarian work, courting wife Amal and his failed baseball dreams. Plus, Dave visits George's folks in Kentucky.
From a Taliban attack to a Nobel Prize to Oxford: Malala Yousafzai walks Dave through her extraordinary journey, her life's mission and her new home.
JAY-Z talks candidly about his past in the streets, his family struggles and racial injustice. David visits legendary producer Rick Rubin in the studio.
Tina Fey opens up about her family, the changing culture at "SNL" and the one moment she wishes she could take back. Plus, blues icon Buddy Guy.
Howard Stern shares the stories behind his outsized radio persona, a heartfelt apology he issued to Dave, and his famous interviews with Donald Trump.
Kanye opens up about family, bipolar disorder, his Sunday Service gatherings and the backlash over his support for Trump. Dave scores new Yeezy gear.
Ellen reflects on some of the toughest and most gratifying moments of her life, and she and Dave make mischief on the set of her talk show.
Tiffany Haddish lights up the stage as she talks Dave through her journey from foster care to the bar mitzvah party circuit to big-time movie roles.
World champion Formula One driver Lewis Hamilton looks back on his scrappy beginnings and gives Dave the thrill of a lifetime on the racetrack.
Melinda Gates breaks down big global challenges and explains why it's vital to get more women in tech. Dave makes sandwiches with her husband, Bill.
Kim Kardashian West walks Dave through key moments from her life, including the O.J. trial, a Paris robbery, her law studies and a White House visit.
The "Iron Man" star opens up about his showbiz childhood, addictions and comeback, then introduces Dave to the animal menagerie at his Malibu home.
In a rare interview near his farm in Ohio, comedy legend Dave Chappelle reflects on his unconventional career, his family and the power of community.
Music superstar Lizzo invites Dave to lay down a track at her home studio as they chat about flutes, protests, her time working with Prince and more.
Dave visits Billie Eilish to discuss inspiration, influences and imposter syndrome — and even manages to work in a little go-karting and Auto-tuning.
Will Smith recalls his rap origins, the lasting impact of his parents, spiritual explorations, and one very fateful night at Quincy Jones' house.
Cardi B and Dave split a chopped cheese in a Bronx bodega and chat hooky parties, hip-hop, parenting, political science and protesting injustice.
Ryan Reynolds makes pizza for Dave while he discusses his youth in Canada, early days as an actor, life as a father and love of Welsh football.
Dave and Kevin Durant go one-on-one in basketball, shuffleboard and conversation as they cover family, focus, trash-talking, social media and more.
Julia Louis-Dreyfus takes Dave fishing and talks growing up with two families, serving Gumby tea on "SNL" and reality overtaking fiction with "Veep."
Miley Cyrus performs an intimate show at the Chateau Marmont and opens up to Dave about songwriting, sobriety and separating herself from Hannah Montana.
Charles Barkley goes golfing with Dave and shares his unfiltered opinions on the NBA and WNBA, his transition to analyst and the fight against racism.
Over donuts and duckpin bowling, Caitlin Clark and Dave discuss her record-breaking rise to WNBA stardom and learning to hone her competitive drive.
Complete episode guide for My Next Guest Needs No Introduction with detailed information about every season and episode including air dates, summaries, ratings, and streaming availability in United States.
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