Devil in Ohio follows hospital psychiatrist Dr. Suzanne Mathis, who shelters a mysterious cult escapee, Mae. Her world is turned upside down as the strange girl's arrival threatens to tear her own family apart.When 15 -year-old Jules Mathis comes home from school to find a strange girl sitting in her kitchen, her psychiatrist mother reveals that Mae is one of her patients at the hospital and will be staying with their family for a few days. But soon Mae is wearing Jules' clothes, sleeping in her bedroom, edging her out of her position on the school paper and flirting with Jules' crush. And Mae has no intention of leaving.
After a teen girl with a strange wound is found in Amon County, Ohio, she is taken to the hospital in a nearby town and put in Dr. Suzanne Mathis' care.
Mae adjusts to life with the Mathis family while Suzanne tries to find her a foster home. Detective Alex Lopez makes an unsettling discovery.
After enrolling in Jules' school, Mae attracts attention from the newspaper editor. Suzanne reaches out to Mae's parents. Peter asks a friend for help.
Alex digs for answers about Amontown and Suzanne consults an expert. Jules' photo of Mae causes a stir at school, with unexpected consequences.
Suzanne gains more clarity on what Mae experienced at Amontown. Halloween night doesn't go as planned for Jules, who begins to question Mae's motives.
Alex makes a key connection after the fire. Painful memories surface for Suzanne. A fearful Mae tries to stop Jules from going on a date.
The night of the Harvest Dance brings a full moon and chaos as Suzanne desperately tries to keep Mae safe. Alex realizes the cult's powerful influence.
Suzanne follows Mae to the Amontown compound, where the Dodd family and their followers prepare for a deadly ritual. The Mathises seek a fresh start.
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